Unorthodox mitosis in Trichonympha agilis: kinetochore differentiation and chromosome movement.
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چکیده
منابع مشابه
Trichonympha burlesquei n. sp. from Reticulitermes virginicus and evidence against a cosmopolitan distribution of Trichonympha agilis in many termite hosts.
Historically, symbiotic protists in termite hindguts have been considered to be the same species if they are morphologically similar, even if they are found in different host species. For example, the first-described hindgut and hypermastigote parabasalian, Trichonympha agilis (Leidy, 1877) has since been documented in six species of Reticulitermes, in addition to the original discovery in Reti...
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The kinetochore is a dynamic multiprotein complex assembled at the centromere in mitosis. Exactly how the structure of the kinetochore changes during mitosis and how its individual components contribute to chromosome segregation is largely unknown. Here we have focused on the contribution of the Mis12 complex to kinetochore assembly and function throughout mitosis in Drosophila. We show that de...
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Proper chromosome segregation in mitosis requires tethering of spindle microtubules to the kinetochore. Using electron tomography of mammalian cells, McIntosh et al. (2008) now report the presence of fibrils that connect the inner kinetochore to the curved protofilaments at microtubule ends, suggesting a new model for force generation in chromosome movement.
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عنوان ژورنال:
- Journal of cell science
دوره 13 2 شماره
صفحات -
تاریخ انتشار 1973